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In contrast, intravenous (IV) blood sampling techniques, such as collection from the tail, jugular, or saphenous veins, are non-terminal and suited for serial sampling in longitudinal studies 16

Perhaps to double down on their threat to CBS to end the series, Reed and Owen's production company inserted a "back-door" pilot for a new series--"The Wide Open Spaces" (March 8, 1962) late in Season 4 as a potential replacement for The Donna Reed Show

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