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Whereas most of the included studies were varied in quality from low to high, most studies had small sample size and only two had large sample size, participants were predominantly male, used different comparison groups, done at different settings, most of the studies were done in the USA, and some of the studies did not report the related findings of NRT effect

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One study showed that even when smokers' homes were cleaned and prepared for sale, third-hand smoke was still present in the dust and on surfaces in the household several months after someone last smoked in the home