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Availability of data and materials All data generated or analyzed during this study are included in this published article

The study participants were divided into three groups: vapers who had never smoked cigarettes

Bars were formed by cooling the hot soap mixture in a large rectangular mold and then cutting the block into individual bars

When they receive their membership card, the designated household member must live at the same address as the Primary or Affiliate Member and must have their photo taken and added to their card

The safety analysis will use the safety population.At each time point, descriptive analyses will be performed to show the two groups of different means (SD and 95% CI) and the rate of outcome change