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The device enables us for the first time to compare responses of human small airway tissues, from both normal individuals and COPD patients, before and after they are exposed to cigarette smoke delivered through physiological breathing outside the human body, explains Donald Ingber, the founding director of the Wyss Institute and the lead researcher of the study

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However, considerable variations remain prevalent across NHS England Regions, from 16.0% in Cumbria and North East to 4.9% in London

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