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The most common causes are: trauma from ill-fitting dentures or braces, biting the inside of the cheek, tongue, or lip, and surgery chemotherapy treatment for cancer viral infection, such as herpes yeast infection, such as thrush any condition associated with xerostomia, or dry mouth smoking or chewing tobacco Other examples include: bacterial infections sexually transmitted infections weakened or deficient immune system irritation from strong chemicals stress certain diseases, including Behcets disease, Crohns disease, and lupus medications, including sulfa drugs, anti-epileptics, and some antibiotics nutritional deficiencies allergic reactions burns caused by hot food and drink It is important to identify the cause of stomatitis in order to treat it properly