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Vidals Interactions mdicamenteuses comprises four seriousness grades according to the recommended clinical managementcontraindicated, avoid, precaution, and take into account (i.e., no specific recommendation) (Les interactions mdicamenteuses, 2024)

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Because the association between CUD and oral cancer remained even after controlling for smoking status, and because CUD was associated with greater oral cancer risk even when the analysis was restricted to smokers, the researchers hypothesize that there may be other factors underlying this risk in addition to smoke inhalation