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J Headache Pain 10(2):121124 Straube A, Pfaffenrath V, Ladwig KH, Meisinger C, Hoffmann W, Fendrich K et al (2010) Prevalence of chronic migraine and medication overuse headache in Germanythe German DMKG headache study

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In the study, mice were exposed five days a week to unflavored e-cigarette aerosol from a vape pen, with or without nicotine (an addictive substance found in tobacco products), for four months