Users typically place a paper tube onto one end of the machine, fill the tobacco chamber with their desired amount of tobacco, and then push or pull a lever or handle to inject the tobacco into the tube
However, the authors note several limitations, including the cross-sectional study design, the exclusion of female participants due to cultural constraints, the relatively small number of bronchial biopsies, and the restriction to Kurdish ethnicity, which may limit generalizability
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For example, when the mucous membrane which is a mucus-secreting tissue inside the nose dries, crusts, or cracks, it will cause bleeding
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