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Biological (Physical) Link of Nicotine AddictionWhat is it?Addiction occurs when a substance like nicotine, alcohol or cocaine enters the brain and activates the brains receptors for that substance, producing pleasure

Why would you question anything

You become dependent, so when you are not smoking and your blood nicotine levels drop, you start to get withdrawal symptoms

Page 431 contains a reprinting of Oliver Wendell Holmes's poem to Twain on his 50th birthday (1885), which first appeared in The Critic on November 28, 1885, and was apparently never collected in Holmes's published poems

This group receives two capsules per day to match the topiramate dosage (placebo in the morning and naltrexone in the afternoon)