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Clearly the excise has gotten over a threshold and triggered an illicit market reaction. Holden said it would take more than a tweak to the excise rate to remove the incentive to buy and sell illegal tobacco, suggesting a radical excise reduction for two years

Acetaldehyde: This chemical is another byproduct of tobacco smoke

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doi:10.1136/tc.2005.013268

That's troubling since adolescents who use Juul e-cigarettes do so on a more regular basis than adolescents who use other forms of e-cigarettes, according to the studys senior author and Stanford professor Bonnie Halpern-Felsher