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Some variations were observed: The age group 1929 showed smaller differences between currently and formerly smoking individuals

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Data compiled by the Department of Defense indicates smokeless tobacco is used by approximately one-fifth of 18- to 24-year-old military males which is twice the national average despite that fact that chewing tobacco is not a safe alternative to smoking

These contribute to oxidative stress and damage epithelial cells by inducing peroxidation of lipids and other cell membrane constituents, activate oxidative-sensitive cellular pathways, and induce DNA damage [35]