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Risks are confounded by the co-administration of nicotine in smoking, often making it hard to separate the actual risk of the cannabis from the tobacco

This system plays a role in pain modulation, which explains why smokers experiencing pain often consume more analgesics, including opioids, to achieve comparable relief

Higher scores indicate that treatment of withdrawal symptoms, usually with nicotine replacement therapy, will be an important factor in the patient's plan of care

The safety and effectiveness of Prozac in children younger than 18 years of age has also not been established

Getting help to stop smoking The NHS offers support to help you stop smoking