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Proper medical guidance with gradual tapering is essential to avoid withdrawal and ensure safe cessation

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Genetic and Epigenetic Aberrations It has been indicated that smoking promotes the genetic and epigenetic aberrations in spermatozoa, such as oxidative DNA damage, chromatin packing disorder, alterations in chromosomes, mutations or/and/or polymorphisms, epigenetic changes (DNA methylation), dysregulation of mRNA expression, which certainly influences sperm functions and male fertility

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