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2018;13(4):e0195774

Current smokers are four times as likely to get the disease as non-smokers, and former smokers face double the risk for bladder cancer

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After a year spent perfecting the design, he said, sales took off and by 2006 Ruyan was producing 24 hours a day with demand still exceeding supply. But that same year, media reports that described his products as addictive and causing heart attacks dented sales