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More recently, a study revealed that while the use of nicotine/flavour-containing e-cigarettes led to significant cytokine dysregulation and potential inflammasome activation, none of these effects were detected in non-flavoured and non-nicotine-containing e-cigarettes [43]

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It seems like the key points are to make the ophthalmologists aware of the potential danger of heavy sedation and non-fasting and to make local guidelines that take into account the type of surgery, type of local and regional anaesthesia, the need for sedation and the possibility of having to convert a failed regional anaesthetic to a general one