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Passive (a.k.a., experimenter-administered) exposure allows for the control of both dose and time of administration relative to other outcome measures (e.g., examination of brain activation after a discrete time period) (60)

This is even true for people who regularly use tobacco and may have had nicotine stomatitis for decades

If you smoke your first cigarette more than 30 minutes after waking up use 2 mg nicotine lozenge according to the following 12-week schedule: Weeks 1 to 6: One lozenge every 1 to 2 hours