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Further, our current findings corroborate conclusions drawn from previous studies done by us and others in the field [19, 21, 22, 32, 33] that indicate that IQOS is as detrimental to pulmonary health as are combustible cigarettes

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Table 3 Dyspnoea-12: a validated 12-item breathlessness assessment questionnaire with scores ranging from 0 to 36, where higher scores indicate greater dyspnea severity

Further, periplasmic nitrate reductases gene nap A, nap B, and nap C were prevalent in the DH and MS products