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There is evidence female vascular biology (hormone-modulated) can react in ways that magnify some of these smoking-induced cardiovascular harms, which helps explain higher relative CHD risk in female smokers

Among these, flavonoids in tobacco leaves are synthesized through pathways such as flavone and flavonol biosynthesis, as well as the phenylpropanoid pathway, under the action of various enzymes, including flavonol synthase (FLS) and phenylalanine ammonia-lyase (PAL) [15]

Combustible cigarettes still contribute the lion share in the revenues of tobacco industry, but its volumetric growth is on the decline, which is made-up by these innovative offerings, which are available in an array of sleek design and cater for numerous taste buds with varied flavors