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Ozone can be harmful to humans and animals if inhaled in high concentrations

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And thats before you start looking at property damage (three housefires a day in London alone are directly attributable to lit tobacco), pollution, etc caused by lit tobacco that either arent applicable to reduced risk products (Im quite sure Snus hasnt started any house fires, ever) or are massively reduced (The fact that battery fires related to e-cigs are newsworthy is testament to how rare they are notice how you dont see news stories about cigarette fires) by these products

LoPachin RM, Gavin T

Smoking remains one of the largest risk factors for disease globally and is a major contributor to the gap in life expectancy and years lived in good health between the richest and poorest groups