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Conclusions Collectively, these findings emphasize brain regions (e.g., ventromedial PFC, insula, thalamus) critically linked with cigarette smoking, suggest neuroimaging paradigms warranting additional consideration among smokers (e.g., pain processing), and highlight regions in need of further elucidation in addiction (e.g., cerebellum)

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Women are significantly more likely than men to prefer capsule cigarettes in many countries

Smokers themselves, they went looking for a way to make cigarettes less carcinogenic and foul-smelling, and more socially acceptable