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As a result of the landmark 2009 Family Smoking Prevention and Tobacco Control Act, the FDA was tasked with regulating not just cigarettes, but a range of tobacco products

Statistical methods The analysis plan was pre-registered on the Open Science Framework ( We report mean and standard deviation for continuous measures that are approximately symmetric, and median and quartiles if the distribution is skewed

Novel hypoglycemic agents, SGLT2i and GLP1RA have also shown anti-inflammatory, antioxidant, mucus secretion reduction and airway remodeling effects in animal models, but there are no clinical studies to demonstrate their role in COPD patients without diabetes

Some studies suggest nonallergic asthma may be among risk factors for severe illness from COVID-19

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