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Nicotine is a vasoconstrictor which means that it shrinks blood vessels

The OXPHOS system consists of four enzyme complexes of the electron transport chain (ETC): NADH:ubiquinone oxido-reductase or NADH dehydrogenase (complex I), succinate dehydrogenase (complex II), coenzyme Q: cytochrome c oxido-reductase or cytochrome bc 1 (complex III), cytochrome c oxidase (complex IV) and ATP synthase (also called complex V)

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