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Although they eliminate some combustion-derived toxins, they still deliver harmful substances capable of inducing oxidative stress, mitochondrial dysfunction, inflammation, and hepatocellular injury

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Statistical analysis showed that there was a statistically significant difference in the amounts and percentage of nicotine between cigarettes randomly chosen from four different packs of each domestic brand

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In the case of IBDs, there can also be nonspecific intestinal and systemic symptoms (eg, weight loss, fever, nausea/vomiting, and fatigue), as well as extraintestinal manifestations (EIMs) (eg, arthritis)