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[49] This led the authors of the study to conclude that "inhalational exposures of cinnamaldehyde may increase the risk of respiratory infections in e-cigarette users." [49] Some e-liquids containing cinnamaldehyde stimulate TRPA1, which might induce effects on the lung

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"The dramatic spikes in youth e-cigarette use back in 2017 and 2018, primarily driven by JUUL, showed us how quickly e-cigarette sales and use patterns can change," said Deirdre Lawrence Kittner, director of the CDC's Office on Smoking and Health