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Moreover, the competitive selective nACh receptor antagonist hexamethonium inhibited sensory nerve stimulation in response to TS, but had no effect on other tussive stimuli, indicating a role for nicotine in the smoke-induced irritant response in dogs (Lee et al., 1983, 1985, 1986, 1989

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Furthermore, a study conducted by San Diego State University found that the chemicals released by cigarette butts are toxic to fish and certain marine animals

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