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The results were highly instructive: At the 100 ng/mL threshold zero non-smoker positives At the 75 ng/mL threshold zero non-smoker positives At the 50 ng/mL threshold (the DOT initial screening standard) only a single positive occurred, even in a sealed unventilated room with heavy smoke At a 20 ng/mL threshold multiple positives occurred Maximum THC metabolite concentrations for non-smokers by GC-MS ranged from 1.3 to 57.5 ng/mL under extreme unventilated conditions The key takeaway: for someone who does not smoke to fail a drug test due to secondhand smoke, they would need to be exposed to a high concentration of smoke in an unventilated space for a prolonged period

Loss of functional p53 disrupts cell cycle arrest and apoptosis, allowing cells with DNA damage to proliferate uncontrollably (Scheffner et al., 1993)

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This spring, Juul Labs agreed to pay more than $400 million to settle claims that its advertising targeted adolescents

NC Rail-Trails then commissioned a study, which found dramatic improvement