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These vulnerable populations and others like them are already more likely to smoke cigarettes and have an especially difficult time quitting

Decreased signs of nicotine withdrawal in mice null for the Beta4 nicotinic acetylcholine receptor subunit

30 E-cigarettes are sold in over 15,000 fruit, candy, and other flavors, 31 including flavors like tobacco, menthol, mint, banana, pia colada, chocolate, and many others

The brand's warning label states the product is not intended for use by "minors, women who are pregnant or breastfeeding, or persons with or at risk of heart disease or high blood pressure." "If you do not currently use nicotine, ZYN is not for you," the brand's website declares

This is primarily due to late detection of the disease