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This could have introduced some selection bias

Initially (pre-21st century), cigarettes were used for their "medicinal properties." However, mounting research and evidence show that these properties were often a byproduct of their addictive properties and placebo effects

This is often related to disruptions in the digestive tract and generally peaks around two weeks but can remain a problem for up to four weeks, according to an older study

Regardless, cessation therapy should be tailored to the specific patient

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