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Most of the nicotine in a cigarette is destroyed by combustion or remains in the sidestream smoke that you do not inhale

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Various targeted sequencing panels have recently been developed to efficiently determine tumour mutation burden, and a strong correlation has been observed between targeted sequencing and whole genome sequencing in some studies.31 32 Another limitation of our study was recall bias, which cannot be ruled out when obtaining smoking information, even in a prospective cohort study