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doi: 10.1164/rccm.201811-2087OC 105

Thus, unlike the equivalent subset in ILC3s, CD4 + CD45RO + ILC1s are not specifically expanded in the blood of smoking patients with asthma

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Among these mediators, TGF-1 is particularly significant, as it directly activates HSCs and stimulates the synthesis of extracellular matrix proteins, thereby promoting fibrogenesis

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