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Lille 1, Villeneuve dAscq, France Laure Saujet, Pherecydes Pharma, Romainville, France Pierre Boudry, Universit Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette, France This article was submitted to Microbial Physiology and Metabolism, a section of the journal Frontiers in Microbiology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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According to Health Canada, by 2012 the national numbers had dropped to 16 percent