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Heavy cigarette smokers have had trouble with the intense volume of smoke and the high nicotine content

As legal tobacco prices have soared, criminal networks have profited by undercutting legal products, offering smokers a cheaper alternative that circumvents regulation and taxation

Some e-cigarette users also report a feeling of pressure or discomfort in the lower abdomen while urinating

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"Today, I'm pursuing actions aimed at addressing the disturbing trend of youth nicotine use and continuing to advance the historic declines we've achieved in recent years in the rates of combustible cigarette use among kids," Gottlieb says