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though treatable, adherence to treatment is difficult for many active drug users, leading to chronic illness Human immunodeficiency virus (HIV) compromises the immune system and can progress to acquired immunodeficiency syndrome (AIDS) Syphilis frequently occurring alongside HIV in IV drug users, particularly because of risky sexual behaviors associated with drug use Acquired immunodeficiency syndrome (AIDS) the advanced stage of HIV infection, severely weakens the immune system, making the body vulnerable to other life-threatening diseases and often leading to death While many of these diseases remain incurable, early intervention and consistent treatment can control most of them effectively, preventing them from being fatal

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