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Mitochondria selective autophagy-lysosomal degradation, known as mitophagy, plays a crucial role in degradation of damaged mitochondria and is mainly governed by posttranslational modifications of phosphatase and tensin homolog (PTEN)-induced putative protein kinase 1 (PINK1) and Parkinson disease 2 (PARK2) [4,5,6,7,8]

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In addition, the fact that high COHb levels can be found even in completely asymptomatic patients (see case 3) demonstrates the dangerous and unpredictable nature of carbon monoxide poisoning

E., Tang, M.-T

doi: 10.1186/s12916-019-1351-4 9