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Such pre-exposure is a standard procedure to guarantee habituation to the exploratory component of the animals behaviour in the open arm, thereby leaving only the aversive component to be evaluated during the first exposure to the mazes open arm 40

Related: Panel considers heat-not-burn cigarettes For men, smoking one cigarette a day on average raised the risk of heart disease by 48 percent over a non-smoker, while smoking 20 cigarettes a day doubled the risk