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Matthew Stevenson, investigative and mechanistic toxicity senior manager and study coauthor, commented: Its encouraging to see the reduced levels of toxicants in our nicotine pouch products compared to combustible cigarette smoke translating directly into substantially reduced in vitro biological responses.

The potential impact of short- and long-term exposure to next - generation tobacco and nicotine products on the development of endothelial dysfunction and its clinical implications for cardiovascular diseases are discussed

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