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Although it could potentially be of serious concern to heavy caffeine users -- defined by the Mayo Clinic as 500 to 600 mg

PMI has carefully overhauled its image with a new mission: "designing a smoke-free future." Since 2008, PMI has invested more than $6 billion on iQOS, its heated tobacco device and other next-generation products

The market must contend with the potential migration of its target consumers to these alternative products and the necessity to retain health-conscious individuals seeking a transition product within the RYO category

Mixing nicotine and caffeine isn't safe

That strategy is a primary driver of the companys ability to achieve gross margins significantly above the industry average, enriching shareholders often at the expense of customers