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These interventions may include raising awareness, stricter regulations and alternative coping mechanisms for mental health, the researchers wrote, with increased knowledge about the negative impacts of e-cigarette use enabling individuals to make informed decisions and discourage adolescents from initiating or continuing their use

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Regardless of how nicotine is absorbed, once this chemical enters the bloodstream, it circulates throughout the body and travels to the brain, where it crosses the blood-brain barrier

British Heart Foundation - Benefits of quitting smoking

(2025a)