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In addition, the dose of nicotine contained in the electronic cigarettes or amount consumed by the participants was not recorded or standardized, which may have confounded the correlation with depressive symptoms

However, it is important to consult with a healthcare provider before discontinuing naltrexone, as stopping the medication increases the risk of relapse into opioid or alcohol use

Given the rising prevalence of E-Cig use during pregnancy, urgent public health interventions are needed

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