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Islam declares all those items and practices makruh or undesirable, which may harm the health but are neither usually fatal, nor lead to any physical handicap like blindness, paralysis etc

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Specifically (Table 5), compared with corresponding adult counterparts who initiated before age 18, the number of different substances used was 5% lower (IDR = 0.95, 95% CI = 0.930.97) among those who initiated alcohol at ages 2129 and 64% lower (IDR = 0.36, 95% CI = 0.340.38) among those who never used alcohol