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RCTs are superior to observational studies with respect to internal validity, but a strength of observational studies is that they reflect the effectiveness of e-cigarettes as they are being used in real-world settings, rather than how a specific device would perform under controlled or optimal conditions

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Now if we think about tobacco in the same way, Hart says, the people who are gonna pay the price are the same people who pay the price poor people. Indeed, nearly three-fourths of all US smokers come from lower socioeconomic statuses, with those below the poverty line twice as likely to smoke as those above it

Dimensions: 7016 x 4701 px | 59.4 x 39.8 cm | 23.4 x 15.7 inches | 300dpi Date taken: 27 August 2011 More information: This image could have imperfections as its either historical or reportage.