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The European tobacco market is characterized by well-established players such as Gallaher Group, British American Tobacco, and Philip Morris International, as well as several small and medium players such as Korea Tobacco & Ginseng Corporation, Imperial Brands, and Swedish Match Europe
Lastly, we are proposing to codify two scenarios when the manufacturer reports negative or zero ASP for all NDCs for a biosimilar for a given quarter: (1) when positive ASP data is available for another biosimilar(s) with the same reference product for the given quarter, we are proposing to set the payment limit equal to the sum of the volume-weighted average of the positive ASP data from all other biosimilars referencing the same ( reference product plus 6 percent (or 8 percent for a qualifying biosimilar biological) of the amount determined under section 1847A(b)(4) of the Act for the reference biological product for the given quarter
Clofazimine, originally an anti-leprosy antibiotic, is now recommended as a core drug in both short and long regimens for DR-TB
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