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COX-2 produces prostaglandin-E2 (PGE 2 ), which promotes angiogenesis and tumor growth (Sahu et al

They deliver about the same nicotine as a cigarette in over 80 puffs, which provides over 10 minutes of keeping your hands busy and mouth occupied, though for some users this may take too long

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Being attractive to the opposite sex is related to social image, and for some middle adolescents (high school age), smoking is thought to make this goal more attainable (2, 3)