Diacetyl can also cause irritation of the respiratory tract when inhaled, even at lower concentrations than those required to cause bronchiolitis obliterans
Notably, exposure to nicotine-free e-vapor induces significant metabolic alterations and liver injury in dams and progeny, whereas nicotine-containing e-vapor promotes hepatic steatosis in adult offspring [135]
Health officials will likely always tout abstinence from any drug (be it tobacco, alcohol, or cannabis) as the safer alternative
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