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Policymakers interested in increasing tax rates should recognize the unintended consequences of high taxation rates

However, while SLT products may pose less harm than conventional cigarettes, they are associated with increased risk for illnesses including oral cancer, esophageal cancer, pancreatic cancer, and heart disease, among others [58]

(2) A generic drug approved under an Abbreviated New Drug Application ( (ANDA) under section 505(j) of the FD&C Act (section 505(j) ANDA), in the case where: (i) The reference listed drug approved under an NDA under section 505(c) of the FD&C Act, including any authorized generic drug as defined in section 505(t)(3) of the FD&C Act, is not being marketed, as identified in the Food and Drug Administration's (FDA) NDC Directory

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Trends in smokeless tobacco use and initiation: 2002 to 2014