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According to Billings the very wealthy owned brushes with silver tips![10] Snuff containers from the mid-19th century, either jars or boxes, have been difficult to locate and identify, even after consulting the Museum of Tobacco Art and Culture in Nashville

Body mass index (BMI) was calculated by dividing weight in kilograms by height in meters squared (kg/m 2 )

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Figure 3 shows that the most commonly reported symptom was bloating (66.7%), followed by nausea (47.9%), heartburn (46.7%), stomach pain (46.5%), and constipation (45.3%), with diarrhea being the least reported (36.6%)