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Association between insulin resistance and the development of cardiovascular disease

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e-cigarette use is associated with a short-term increase in systolic blood pressure, changes in biomarkers of oxidative stress, increased endothelial dysfunction and arterial stiffness, and autonomic control

Instead of modelling risk with consumption for each study (which is non-linear), we modelled the logarithm of risk, using similar methods as before.1214 This involved fitting a log-linear variance weighted regression model between incidence or relative risk and cigarette consumption (using all reported smoking categories in the publications)