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Therefore, less activity in DLPFC reduces these cognitive operations, making relapse more likely. People in the relapse group also had reduced suppression of activation in the posterior cingulate cortex (PCC), a central part of the brains default mode network, which is active when a person is not focused on a specific task

The AORs and p-values were calculated using multiple Firths penalized likelihood logistic regression analyses with adjustment for age, physical activity, alcohol intake, body mass index, estimated glomerular filtration rate, diabetes, hypertension, and dyslipidemia