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In addition, NHIS collects information on the use of cigarettes and cigars only once at survey enrollment for each participant, and information on alcohol use and preexisting chronic conditions (e.g., diabetes, high blood pressure, high cholesterol), which are risk factors for premature death, was not available consistently after 1997 in NHIS

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Abstract S -6-methyl nicotine ( S -6MN) has appeared as a nicotine substitute in commercial electronic e-cigarette products and pouches, including with the claim that such use is not regulated under current U.S