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Ratios of smoking-attributable cancer deaths by age in Qingdao in 2005, 2010 and 2015.

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The undersigned public health, medical, civil righs and community organizations conclude that the Draft Guidance fails to recognize the well-established history of signficant variations in youth flavor preferences over time, often caused by regulatory decisions, and this fundamental flaw threatens to open the regulatory door to a wide array of FDA-authorized products that would appeal and be accessible to youth, without signficant countervailing health benefits to adults who smoke

A review of the EU Tobacco Products Directive currently under way includes a proposed new regulation which would require any device containing more than 4mgs of nicotine to be authorised as a medicinal product

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